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6/27/10-WFAA.com WFAA-TV|Dallas/Fort Worth - Health News - Zinc danger remains in denture paste

"A lot of my clients were complaining of symptoms and go to their doctors, and the doctors will simply ignore them; they are unaware of the zinc poisoning issues. They are unaware that these products even contain zinc," said Parker Waichman LLP, part of a team of attorneys representing more than 100 plaintiffs in a mass tort. He credits News 8 reports for getting the word out.
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3/10/10-Philadelphia Daily News - Zinc in dental adhesives can cause "horrific injuries," lawyer says.
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Philadelphia Daily News - News coverage of Poligrip dental adhesive.
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GlaxoSmithKline (GSK) warns about a potential health risk associated with long-term, excessive use of GSK?s zinc-containing denture adhesives Super Poligrip ?Original?, ?Ultra Fresh? and ?Extra Care?.
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Press Release - 2/18/2010 - Parker Waichman LLP Commends GlaxoSmithKline for its Decision to Voluntarily Stop the Manufacture, Distribution and Advertising of all Super PoliGrip Denture Cream Products Made with Zinc.

Consumer Web Advisory - 2/18/2010 - GlaxoSmithKline (GSK) warns about a potential health risk associated with long-term, excessive use of GSK's zinc-containing denture adhesives Super Poligrip 'Original', 'Ultra Fresh' and 'Extra Care'.

ABC News - Study Finds a Possible Link Between Denture Cream and Imbalance

For More Information About The Poligrip Lawsuit - Click Here

GlaxoSmithKline Stops Making 3 Super PoliGrip Products Because of Zinc Risks

The risk of zinc poisoning prompted GlaxoSmithKline to announce it would voluntarily stop manufacturing, marketing and advertising three zinc-containing Super PoliGrip denture cream products on February 18, 2010. The products affected by this announcement are: Super PoliGrip 'Original', 'Ultra Fresh' and 'Extra Care'.

Glaxo said it is currently in the process of reformulating Super PoliGrip 'Original', Super PoliGrip 'Ultra Fresh' and Super PoliGrip 'Extra Care' to non-zinc formulations. The new versions should be in stores by Mid April 2010.

A small amount of zinc is necessary for a balanced diet. However, recent research suggests that long-term excessive use of zinc-containing denture creams like the Super PoliGrip products may lead to the development of neurological symptoms. These may include numbness, tingling or weakness in the arms and legs, difficulties with walking and balance and blood problems such as anemia.

Glaxo maintains that Super PoliGrip 'Original', 'Ultra Fresh? and 'Extra Care' are safe to use as directed, but noted that some consumers may apply more adhesive than directed, or use it more than once per day. In a statement posted on its Web site, Glaxo said it stopped the manufacture, distribution and advertising of the three zinc-containing Super PoliGrip products as a precautionary measure to minimize any potential risks to consumers. The company also said it had discussed the matter with the Food & Drug Administration (FDA), and no further action is necessary.

According to Glaxo's statement, consumers who have been using zinc-containing Super PoliGrip 'Original', 'Ultra Fresh' or 'Extra Care' for several years in greater amounts than directed on the package or more than once per day, or have concerns about their health, must:

  • Stop using the product.
  • Talk to their doctor.
  • Use a zinc-free alternative.

This action does not affect any zinc-free Super PoliGrip products, including Super PoliGrip 'Free,' Super PoliGrip 'Comfort Seal Strips', or Super PoliGrip 'Powder'. These products remain available to consumers.

Consumers with questions about this action can call Glaxo toll free at 1-866-640-1017.

Copper Deficiency Causes Multiple Sclerosis Symptoms

If you have been diagnosed with Multiple Sclerosis and are a denture cream user, you should know that there is a possibility that you have been misdiagnosed. Denture creams have been known to cause copper deficiency, a condition that, when severe, has much in common with Multiple Sclerosis.

A copper deficiency can cause Multiple Sclerosis symptoms. Excessive exposure to zinc in denture creams, such as Poligrip and Fixodent, can cause depletion of the body's stores of copper. This can lead to neurological problems that are strikingly similar to those suffered by people with Multiple Sclerosis. Our denture cream injury lawyers have already investigated several cases of misdiagnosed Multiple Sclerosis. In these cases, it turned out that Multiple Sclerosis-like symptoms were actually the result of denture cream copper deficiency.

Untreated copper deficiency can lead to permanent disability. If you or someone you love has used denture cream, and now suffers from symptoms of Multiple Sclerosis, or have been diagnosed with the disease, you should ask your doctor to test the copper levels in your blood. If a test shows that you suffer from copper deficiency, your denture cream could be causing your Multiple Sclerosis symptoms.

If you have been diagnosed with Multiple Sclerosis, or suffer from Multiple Sclerosis-like symptoms, and have used denture cream, you may be entitled to compensation. We urge you to contact one of our denture cream copper deficiency lawyers right away in order to protect your legal rights.

Denture Creams and Copper Deficiency

Like most people, you may not even realize that the denture cream you use could endanger your health. This is because the Food & Drug Administration (FDA) does not require the makers of denture adhesives to warn that using too much of their products could lead to copper deficiency.

Copper is an essential trace mineral needed for good health and wellness. Even a mild case of copper deficiency impairs the ability of white blood cells to fight infection. Copper is necessary for proper absorption of iron in the body, and it is found primarily in foods containing iron. If the body does not get a sufficient amount of copper, hemoglobin production decreases and copper-deficiency anemia can result.

The evidence that copper deficiency from denture cream causes neurological problems similar to those seen with Multiple Sclerosis is mounting. In 2008, researchers at the University of Texas conducted a small study that found a link between neurological symptoms in four patients and their use of denture adhesives. All four patients had been using prodigious amounts of dental cream – an average of 2 tubes per week - for many years.

Normal blood levels of copper range from 0.75 to 1.45 micrograms per milliliter (mL), but levels for the patients in the report ranged from less than 0.1 to 0.23 micrograms per mL. The only risk factor the patients had in common was their excessive use of zinc-containing denture cream. The study determined that excessive exposure to the zinc contained in the dental adhesives the subjects used was most likely behind their copper deficiency and accompanying neurological symptoms.

Similarities Between Multiple Sclerosis, Severe Copper Deficiency

Research has shown that copper deficiency can result in central nervous system demyelination (damage to the myelin sheaths of the neurons). This can lead to the development of the following symptoms:

  • tingling or numbness in the extremities
  • loss of ability to move legs, feet, arms, or hands
  • poor balance and coordination
  • decrease in walking stride
  • abnormal blood pressure and heart rate
  • reduced ability to perspire
  • constipation and bladder dysfunction.

Multiple Sclerosis is one of a group of demyelinating diseases. Others include transverse myelitis, Devic's disease, progressive multifocal leukoencephalopathy, optic neuritis, Guillain-Barre Syndrome and its chronic counterpart, chronic inflammatory demyelinating polyneuropathy, and anti-MAG peripheral neuropathy. As is the case with copper deficiency, these diseases are characterized by damage to the myelin sheath of the neurons.

A person with Multiple Sclerosis may suffer from numbness, tingling, pain or other uncomfortable sensations in the extremities; muscle weakness, muscle spasms, or difficulty in moving; difficulties with coordination and balance; problems in speech or swallowing, visual problems, fatigue, acute or chronic pain, and bladder and bowel difficulties.

It is easy to understand how a case of denture cream copper deficiency could be misdiagnosed as Multiple Sclerosis. The only way to determine if these symptoms are the result of copper deficiency or Multiple Sclerosis is through a blood test.

Other Possible Misdiagnoses of Denture Cream Copper Deficiency

Denture cream copper deficiency has been mistaken for other demyelinating diseases. Some of the most frequent misdiagnoses include:

Demyelinating Syndrome: This syndrome is often associated with other diseases, such as lupus. Typical symptoms include odd sensation in legs, arms, chest, or face, such as tingling or numbness, or weakness; blurriness or double vision; loss of dexterity; and coordination problems.

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP): A rare neurological disorder in which there is swelling of nerve roots and destruction of the myelin sheath over the nerves. This disorder causes weakness, paralysis and/or impairment in motor function, especially of the arms and legs. Sensory loss may also be present causing numbness, tingling, or prickling sensations. The motor and sensory impairments usually affect both sides of the body, and the degree of severity may vary.

Guillain-Barré Syndrome: A disorder in which the body's immune system attacks part of the peripheral nervous system. Early symptoms of this disorder-such as varying degrees of weakness or tingling sensations in the legs-are similar to those caused by zinc copper deficiency. In many instances the weakness and abnormal sensations spread to the arms and upper body. These symptoms can increase in intensity until certain muscles cannot be used at all. When severe, a patient may suffer life-threatening paralysis.

Other Related Links

Excess use of denture cream tied to nerve damage

American Academy of Neurology: An unusual source of excess zinc, leading to hypocupremia and neurologic disease

More claims of denture cream poisoning

Legal Help for Victims of Denture Cream Copper Deficiency

If you or someone you love suspect your Multiple Sclerosis symptoms could actually be the result of a denture cream copper deficiency, you may have valuable legal rights. Please fill out our online form or call 1-800 LAW INFO (1-800-529-4636) as soon as possible to discuss your case with one of our denture cream copper deficiency lawyers.

Parker Waichman LLP is an AV Rated Law Firm Under the Martindale Hubble Peer Review Rating System.

Legal Help for Victims of Fixodent Zinc Poisoning

Our firm is working hard to make sure the victims of Fixodent zinc poisoning are compensated for their pain and suffering. We will make sure that Proctor & Gamble is held accountable for failing to warn of the dangers posed by Fixodent. If you or someone you know are dealing with health problems related to zinc in Fixodent, please fill out or online form, or call 1 800 LAW INFO (1-800-529-4636) to discuss your legal rights.

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